EU SCCS Considers Phytonadione Epoxide Unsafe for Use in Cosmetics

Source: ChemLinked

By: Jarius Ji

On November 5, 2026, the EU Scientific Committee on Consumer Safety (SCCS) issued a preliminary opinion on the safety of Phytonadione Epoxide (CAS No. 25486-55-9) in cosmetic products. The public consultation will remain open until January 11, 2027.1

Phytonadione Epoxide (also known as Vitamin K1 oxide) is primarily used as a skin-conditioning ingredient in cosmetic products, particularly those targeting redness, visible capillaries, and uneven skin tone. It was introduced as an alternative to Vitamin K1 after the latter was prohibited in the EU in 2009 due to reports of allergic contact dermatitis. In recent years, reports of allergic reactions, including severe cases associated with cosmetic use, have raised concerns about the skin sensitization potential of Phytonadione Epoxide. In response, the European Commission requested SCCS to assess its safety in cosmetic products.